Individual variation of the SARS-CoV-2 receptor ACE2 gene expression and regulation. Jiawei Chen^, Quanlong Jiang^, Xian Xia^, Kangping Liu^, Zhengqing Yu, Wanyu Tao, Wenxuan Gong and Jing-Dong J.Three-dimensional facial-image analysis to predict heterogeneity of the human ageing rate and the impact of lifestyle. Xian Xia^, Xingwei Chen^, Gang Wu, Fang Li, Yiyang Wang, Yang Chen, Mingxu Chen, Xinyu Wang, Weiyang Chen, Bo Xian, Weizhong Chen, Yaqiang Cao, Chi Xu, Wenxuan Gong, Guoyu Chen, Donghong Cai, Wenxin Wei, Yizhen Yan, Kangping Liu, Nan Qiao, Xiaohui Zhao, Jin Jia, Wei Wang, Brian K.The precursor of PI(3,4,5)P 3 alleviates aging by activating daf-18(Pten) and independent of daf-16. Dawei Shi^, Xian Xia^, Aoyuan Cui^, Zhongxiang Xiong, Yizhen Yan, Jing Luo, Guoyu Chen, Yingying Zeng, Donghong Cai, Lei Hou, Joseph McDermott, Yu Li, Hong Zhang and Jing-Dong J.Assessing the rate of aging to monitor aging itself. Xian Xia^, Yiyang Wang^, Zhengqing Yu, Jiawei Chen and Jing-Dong J.Aging-associated lncRNAs are evolutionarily conserved and participate in NFκB signaling. De novo generation of macrophage from placenta-derived hemogenic endothelium. Guixian Liang^, Chunyu Zhou^, Xiangxiang Jiang^, Yifan Zhang, Baofeng Huang, Suwei Gao, Zhixin Kang, Dongyuan Ma, Fengchao Wang, Berthold Gottgens*, Hongmei Wang*, Jing-Dong J.Immunosuppression Induced by Brain‑Specific HDAC6 Knockdown Improves Aging Performance in Drosophila melanogaster. Yingying Zhao^, Hongwen Xuan^, Chao Shen, Peiyi Liu, Jing-Dong J.Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans. Xueqing Wang^, Quanlong Jiang^, Yuanyuan Song^, Zhidong He, Hongdao Zhang, Mengjiao Song, Xiaona Zhang, Yumin Dai, Oezlem Karalay, Christoph Dieterich, Adam Antebi, Ligang Wu*, Jing-Dong J.Computational and Structural Biotechnology Journal, May 2022. 3D chromatin structure changes during spermatogenesis and oogenesis. Shiqiang Zhang^, Wanyu Tao^ and Jing-Dong J.Yusheng Cai^, Wei Song^, Jiaming Li^, Ying Jing^, Chuqian Liang^, Liyuan Zhang^, Xia Zhang^, Wenhui Zhang^, Beibei Liu^, Yongpan An^, Jingyi Li^, Baixue Tang^, Siyu Pei^, Xueying Wu^, Yuxuan Liu^, Cheng-Le Zhuang^, Yilin Ying^, Xuefeng Dou^, Yu Chen^, Fu-Hui Xiao^, Dingfeng Li^, Ruici Yang^, Ya Zhao^, Yang Wang^, Lihui Wang^, Yujing Li^, Shuai Ma*, Si Wang*, Xiaoyuan Song*, Jie Ren*, Liang Zhang*, Jun Wang*, Weiqi Zhang*, Zhengwei Xie*, Jing Qu*, Jianwei Wang*, Yichuan Xiao*, Ye Tian*, Gelin Wang*, Ping Hu*, Jing Ye*, Yu Sun*, Zhiyong Mao*, Qing-Peng Kong*, Qiang Liu*, Weiguo Zou*, Xiao-Li Tian*, Zhi-Xiong Xiao*, Yong Liu*, Jun-Ping Liu*, Moshi Song*, Jing-Dong J.KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA–DNA triplexes and HP1 binding. Xiaoli Zhang^, Quanlong Jiang^, Jiyang Li^, Shiqiang Zhang^, Yaqiang Cao, Xian Xia, Donghong Cai, Jiaqi Tan, Jiekai Chen and Jing-Dong J.Transformer for one stop interpretable cell type annotation. Jiawei Chen^, Hao Xu^, Wanyu Tao, Zhaoxiong Chen, Yuxuan Zhao and Jing-Dong J.Trends in Biochemical Sciences, Apr 2023. LncRNAs: the missing link to senescence nuclear architecture. Spatial Reconstruction of Oligo and Single Cells by De Novo Coalescent Embedding of Transcriptomic Networks. Yuxuan Zhao^, Shiqiang Zhang^, Jian Xu, Yangyang Yu, Guangdun Peng,Ĭarlo Vittorio Cannistraci* and Jing-Dong J.Using data-mining, statistics approaches and network theories, we first try to generate biological hypotheses and computational models, and then use molecular biology, cell biology and systems biology approaches to validate and refine models and hypotheses. Genetic robustness or fail-safe mechanisms engineered to genetic networks. Understanding complex human diseases through structure, dynamics and function of disease-related networks. Integration of genomic and functional genomics data to formulate biological hypotheses for human disease-related processes. Email: - present, Center for Quantitative Biology, Peking University.Ģ010 - 2018, CAS-MPG Partner Institute for Computational Biology (PICB), SIBS, CAS.Ģ005 - 2010, Institute of Genetics and Developmental Biology, CAS.Ģ002 - 2004, Postdoc, Dana Farber Cancer Institute and Harvard Medical School.ġ999 - 2002, Software engineer (North Star, Rare Medium and CQOS).ġ997 - 1998, Postdoc, The Rockefeller University.ġ996, Ph.D., Albert Einstein College of Medicine.ġ991, B.S., China Pharmaceutical University.
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